Benzenesulfonyl chloride is an organosulfur compound with the formula C 6 H 5 SO 2 Cl. It is a colourless viscous oil that dissolves in organic solvents, but reacts with compounds containing reactive N-H and O-H bonds. It is mainly used to prepare sulfonamides and sulfonate esters by reactions with amines and alcohols, respectively.
The gas-phase fluorine migration reactions of radical cations of benzenesulfonyl fluoride have been studied by electron ionization tandem mass spectrometry. Application Benzenesulfonyl fluoride has been used in the preparation of α-sulfonyl phosphonates by direct sulfonylation of …
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In what solvents is Product A8456, 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, soluble? It is highly soluble in water and in DMSO, at 50 mg/mL (approximately 200 mM), yielding a clear colorless solution. AEBSF may be used in cell culture medium at concentrations up to 0.25 mM.
Hydrofluoric acid is a solution of hydrogen fluoride (HF) in water.It is used to make most fluorine-containing compounds; examples include the pharmaceutical fluoxetine (Prozac) and the material PTFE (Teflon). Elemental fluorine is produced from it. Solutions …
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials .
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1 .
In addition, several potent peptide chloromethyl ketone and substituted benzenesulfonyl fluoride irreversible inhibitors for these enzymes were discovered. The most potent sulfonyl fluoride inhibitor for RMCP I, RMCP II, and human skin chymase, 2-(Z-NHCH2CONH)C6H4SO2F, had kobsd/[I] values of 2500, 270, and 1800 M-1 s-1, respectively.
4-(2-Aminomethyl)benzenesulfonyl fluoride hydrochloride (AEBSF) is a serine protease inhibitor.1-4 High yield protein purification requires the presence of protease inhibitors to prevent proteolytic degradation and increase the purity of the resultant preparation. Phenylmethylsulfonyl fluoride (PMSF) has …
In addition, several potent peptide chloromethyl ketone and substituted benzenesulfonyl fluoride irreversible inhibitors for these enzymes were discovered. The most potent sulfonyl fluoride inhibitor for RMCP I, RMCP II, and human skin chymase, 2-(Z-NHCH 2 CONH)C 6 H 4 SO 2 F, had k obsd /[I] values of 2500, 270, and 1800 M -1 s -1, respectively.